idursulfase · Medicine question

How does idursulfase work in Hunter syndrome?

iatroX medicinesPublished 8 November 2026

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Idursulfase supplies the deficient enzyme iduronate-2-sulfatase, entering cellular lysosomes through mannose-6-phosphate receptor-mediated uptake to break down accumulated glycosaminoglycans in Hunter syndrome.

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Elaprase 2 mg/ml concentrate for solution for infusionTakeda UK Ltd · emc · SmPC §5.1 Pharmacodynamic properties · Version 21Document updated 7 May 2025

Sources checked 8 November 2026

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By what route is Elaprase (idursulfase) administered?Does idursulfase affect the ability to drive or use machines?How much sodium does each vial of Elaprase (idursulfase) contain?Is idursulfase known to pass into human breast milk?What are the most common infusion-related reactions to idursulfase?What condition is Elaprase (idursulfase) used to treat?

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