Answer
Grapefruit juice is a strong CYP3A inhibitor that may increase ponatinib concentrations, so caution is required and reducing the ponatinib starting dose to 30 mg should be considered when used together.
Sources for this answer
- Ponatinib Incyte 30 mg film-coated tabletsIncyte Biosciences UK Ltd · emc · SmPC §4.5 Interaction with other medicinal products · Version 3Document updated
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