estriol · Medicine question

How does estriol act on atrophic vaginal tissue?

iatroX medicinesPublished 8 November 2026

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Answer

Estriol is a weak oestrogen that binds to oestrogen receptors in the female genital tract, correcting reduced cell proliferation and abnormal physiology in atrophic vaginal epithelium caused by oestrogen deficiency.

Sources for this answer

Gynest 0.01% w/w CreamMarlborough Pharmaceuticals Ltd · emc · SmPC §5.1 Pharmacodynamic properties · Version 3Document updated 13 September 2021

Sources checked 8 November 2026

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