Answer
Gynest estriol cream is applied high into the vagina using a filled applicator containing 5 ml (0.5 mg estriol), preferably in the evening, initially once daily, with maintenance of one applicatorful twice weekly after restoration of the vaginal mucosa.
Sources for this answer
- Gynest 0.01% w/w CreamMarlborough Pharmaceuticals Ltd · emc · SmPC §4.2 Posology and method of administration · Version 3Document updated
Sources checked