ertapenem · Medicine question

How does ertapenem act on bacteria?

iatroX medicinesPublished 8 November 2026

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Answer

Ertapenem inhibits bacterial cell wall synthesis by attaching to penicillin-binding proteins (PBPs), with strongest affinity for PBPs 2 and 3 in Escherichia coli.

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INVANZ 1g powder for concentrate for solution for infusionMerck Sharp & Dohme (UK) Limited · emc · SmPC §5.1 Pharmacodynamic properties · Version 28Document updated 18 November 2025

Sources checked 8 November 2026

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