eptinezumab · Medicine question

How does eptinezumab work to prevent migraine attacks?

iatroX medicinesPublished 8 November 2026

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Eptinezumab is an antibody that binds calcitonin gene-related peptide (CGRP), preventing CGRP receptor activation and the downstream physiological events linked to the initiation of migraine attacks.

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Vyepti 100 mg concentrate for solution for infusion (300 mg not marketed)Lundbeck Limited · emc · SmPC §5.1 Pharmacodynamic properties · Version 4Document updated 26 November 2024

Sources checked 8 November 2026

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Are interactions between eptinezumab and medicines that affect cytochrome P450 enzymes considered likely?Has the effect of eptinezumab on human fertility been evaluated?How much sorbitol and polysorbate 80 does Vyepti (eptinezumab) concentrate contain per mL?What are the most common adverse reactions to Vyepti (eptinezumab)?What is known about using eptinezumab while breastfeeding?What is the recommendation on using Vyepti (eptinezumab) during pregnancy?

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