Answer
In a study, multiple doses of diltiazem increased single-dose naloxegol exposure (AUC) 3.4-fold and peak concentration (Cmax) 2.9-fold compared with naloxegol alone, so naloxegol dose adjustment is recommended.
Sources for this answer
- Moventig 25mg film-coated tabletsGrunenthal Ltd · emc · SmPC §4.5 Interaction with other medicinal products · Version 14Document updated
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