Answer
Darunavir with cobicistat decreases plasma ethinyloestradiol concentrations in users of drospirenone/ethinyloestradiol contraceptives, so alternative or additional contraceptive measures are recommended.
Sources for this answer
- Tybost 150mg film coated tabletGilead Sciences Ltd · emc · SmPC §4.4 Special warnings and precautions for use · Version 18Document updated
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