cobicistat · Medicine question

Can cobicistat be taken with simvastatin or lovastatin?

iatroX medicinesPublished 8 November 2026

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Answer

No, Tybost (cobicistat) must not be taken with simvastatin or lovastatin because increased plasma concentrations can cause serious and/or life-threatening events.

Sources for this answer

Tybost 150mg film coated tabletGilead Sciences Ltd · emc · SmPC §4.3 Contraindications · Version 18Document updated 7 June 2023

Sources checked 8 November 2026

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