Answer
A single 45 mg oral dose of dacomitinib monohydrate (Vizimpro) increased dextromethorphan mean exposure measured by AUClast and Cmax by 855% and 874%, respectively, compared with dextromethorphan alone.
Sources for this answer
- Vizimpro 15mg film-coated tabletsPfizer Limited · emc · SmPC §4.5 Interaction with other medicinal products · Version 5Document updated
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