Answer
Clarithromycin, a strong CYP3A inhibitor, increases brensocatib AUC by 55% and peak concentration (Cmax) by 68%, but this effect on systemic exposure is not considered clinically meaningful.
Sources for this answer
- Brinsupri 25 mg film-coated tabletsInsmed Limited · emc · SmPC §5.2 Pharmacokinetic properties · Version 1Document updated
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