Answer
In healthy subjects, celecoxib 200 mg twice daily with lithium 450 mg twice daily increased lithium’s mean peak plasma concentration by 16% and AUC by 18%, so lithium-treated patients should be closely monitored when celecoxib is introduced or withdrawn.
Sources for this answer
- Celebrex 100mg capsuleViatris (formerly Mylan or Upjohn) · emc · SmPC §4.5 Interaction with other medicinal products · Version 27Document updated
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