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Medicines pyrazinamideQuestion & answer

pyrazinamide · Medicine question

How can pyrazinamide affect rifampicin blood levels?

iatroX medicinesPublished 8 November 2026

The answer

Answer

Pyrazinamide may reduce rifampicin blood levels through reduced bioavailability and enhanced rifampicin clearance.

Sources for this answer

Pyrazinamide 500 mg tabletsMorningside Healthcare Ltd · emc · SmPC §4.5 Interaction with other medicinal products · Version 1Document updated 19 June 2025

Sources checked 8 November 2026

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pyrazinamide

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