Answer
Paliperidone in Xeplion may antagonise the effects of levodopa and other dopamine agonists; if the combination is necessary, particularly in end-stage Parkinson's disease, the lowest effective dose of each treatment should be prescribed.
Sources for this answer
- XEPLION 150 mg prolonged release suspension for injectionJanssen-Cilag Ltd (a Johnson & Johnson Company) · emc · SmPC §4.5 Interaction with other medicinal products · Version 4Document updated
Sources checked