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Medicines methotrexate disodiumQuestion & answer

methotrexate disodium · Medicine question

How can omeprazole affect the elimination of methotrexate?

iatroX medicinesPublished 8 November 2026

The answer

Answer

Omeprazole taken with methotrexate can prolong methotrexate elimination via the kidneys.

Sources for this answer

Methotrexate 2mg/ml Oral SolutionRosemont Pharmaceuticals Limited · emc · SmPC §4.5 Interaction with other medicinal products · Version 15Document updated 1 October 2026

Sources checked 8 November 2026

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methotrexate disodium

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