moclobemide · Medicine question

How can moclobemide affect omeprazole exposure?

iatroX medicinesPublished 8 November 2026

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Moclobemide inhibits CYP2C19 and can increase omeprazole concentrations, with a doubling of omeprazole exposure in CYP2C19 extensive metabolisers; caution is needed with concomitant use.

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Manerix 300mgViatris (formerly Mylan or Upjohn) · emc · SmPC §4.5 Interaction with other medicinal products · Version 10Document updated 25 March 2026

Sources checked 8 November 2026

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