Answer
Methotrexate, a potentially liver-toxic medicine, may increase daunorubicin hydrochloride toxicity by impairing its liver metabolism and/or biliary excretion, potentially intensifying its side effects.
Sources for this answer
- Daunorubicin 20mg Powder for InjectionZentiva · emc · SmPC §4.5 Interaction with other medicinal products · Version 7Document updated
Sources checked