Answer
Mefloquine hydrochloride taken with phenytoin may lower phenytoin blood levels and cause loss of seizure control, so adjustment of the anti-seizure medication dose may be necessary.
Sources for this answer
- Lariam 250 mg tablets / Mefloquine 250 mg tabletsNeon Healthcare Ltd · emc · SmPC §4.5 Interaction with other medicinal products · Version 5Document updated
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