Answer
Afatinib dimaleate may increase the bioavailability of oral rosuvastatin and sulfasalazine, which are BCRP substrates; in vitro studies indicate that afatinib inhibits this transporter.
Sources for this answer
- Giotrif 20 mg film-coated tabletsBoehringer Ingelheim Limited · emc · SmPC §4.5 Interaction with other medicinal products · Version 1Document updated
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