tolbutamide · Medicine question

Does tolbutamide pass into breast milk?

iatroX medicinesPublished 8 November 2026

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Tolbutamide has been detected in breast milk in small quantities; its effect on the newborn is unknown, but there is a theoretical risk of hypoglycaemia, so breast-feeding is best avoided while taking it.

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Tolbutamide Tablets BP 500mgSovereign Medical · emc · SmPC §4.6 Fertility, pregnancy and lactation · Version 2Document updated 3 February 2026

Sources checked 8 November 2026

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