methotrexate · Medicine question

Does methotrexate pass into breast milk?

iatroX medicinesPublished 8 November 2026

The answer

Answer

Yes, methotrexate 25 mg/ml Injection passes into breast milk, and because serious adverse reactions may occur in nursing infants, a decision is needed whether to stop nursing or the drug, considering its importance to the woman.

Sources for this answer

Methotrexate 25 mg/ml InjectionHospira UK Ltd · emc · SmPC §4.6 Fertility, pregnancy and lactation · Version 28Document updated 7 September 2026

Sources checked 8 November 2026

Explore this learning need in CPDTake this topic to CPD, then choose your learning context and available question library.

Are methotrexate's effects on fertility reversible after treatment stops?How long must women continue effective contraception after stopping methotrexate?Are pharmaceutical incompatibilities listed for the Morningside Healthcare Ltd methotrexate 2.5 mg tablet product?By which route is the Morningside Healthcare Ltd methotrexate 2.5 mg tablet product administered?By which routes can the Hospira UK Ltd methotrexate 25 mg/ml injection product be administered?

loading page…

Answer

Sources for this answer

More questions about methotrexate

Answer

Sources for this answer

More questions about methotrexate

methotrexate

More clinical questions?