Answer
Yes. These products can increase systemic prednisolone effects, so the combination may need to be avoided or monitored closely.
Sources for this answer
- Prednisolone 20 mg/dose Rectal Foamemc · SmPC Current selected SmPC · Version 7
- Prednisolone 20 mg/100 ml Rectal Solutionemc · SmPC Current selected SmPC · Version 1