Answer
It can provide a clinically important sodium load, although the amount differs between formulations. This particularly matters with salt restriction, hypertension, heart failure, oedema, kidney impairment or prolonged treatment.
Sources for this answer
- NHS Specialist Pharmacy ServiceNHS Specialist Pharmacy Service · NHS medicine guidance
- Sodium Bicarbonate 500 mg Capsules — Current selected SmPCemc · Summary of Product Characteristics