Answer
Mekinist (trametinib dimethyl sulfoxide) should not be given during breastfeeding because milk excretion is unknown and infant risk cannot be excluded; a decision must be made to stop breastfeeding or trametinib, considering breastfeeding benefits for the child and treatment benefits for the woman.
Sources for this answer
- Mekinist film-coated tabletsNovartis Pharmaceuticals UK Ltd · emc · SmPC §4.6 Fertility, pregnancy and lactation · Version 30Document updated
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