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Medicines aprotinin + calcium chloride + human fibrinogen + human thrombinQuestion & answer

aprotinin + calcium chloride + human fibrinogen + human thrombin · Medicine question

Can TISSEEL be used during pregnancy?

iatroX medicinesPublished 18 August 2026Reviewed 18 August 2026

The answer

Answer

Pregnancy safety has not been established in controlled trials. It should be used only when the surgical team considers it clearly needed.

Sources for this answer

TISSEEL Ready to use Solutions for Sealantemc · SmPC Current selected SmPC · Version 7

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The full medicine guide

aprotinin + calcium chloride + human fibrinogen + human thrombin

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