Answer
Yes. Travoprost may gradually increase brown pigmentation in the iris, and the change can be permanent, particularly when only one eye is treated.
Sources for this answer
- Travoprost/Timolol Mylan 40 micrograms/ml + 5 mg/ml eye drops, solution — Current selected SmPCemc · Summary of Product Characteristics
General medicine information. Follow the instructions for your own medicine and speak to a pharmacist or clinician about your individual circumstances.