temozolomide · Medicine question

Can temozolomide be used during pregnancy?

iatroX medicinesPublished 8 November 2026

The answer

Answer

Temodal (temozolomide) should not be administered during pregnancy; if its use must be considered, the patient should be informed of the potential risk to the foetus.

Sources for this answer

Temodal CapsulesMerck Sharp & Dohme (UK) Limited · emc · SmPC §4.6 Fertility, pregnancy and lactation · Version 37Document updated 3 August 2023

Sources checked 8 November 2026

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How long must women of childbearing potential use effective contraception during and after temozolomide treatment?Can women breastfeed while receiving temozolomide?How does valproic acid affect the clearance of temozolomide?How much anhydrous lactose does each Temodal (temozolomide) 100 mg hard capsule contain?Is temozolomide contraindicated in people with hypersensitivity to dacarbazine?What risk may increase when temozolomide is combined with other myelosuppressive medicines?

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