Answer
Some antidepressants can increase seizure risk, and serotonergic antidepressants have been associated with serotonin syndrome. The combination requires prescriber review.
Sources for this answer
- Tapentadol Aspire 250 mg prolonged-release tablets — Current selected SmPCemc · Summary of Product Characteristics
- Tapentadol Neuraxpharm 150 mg prolonged-release capsules, hard — Current selected SmPCemc · Summary of Product Characteristics