Answer
Yes. Repeated opioid use can cause tolerance, physical dependence and opioid use disorder. Speak to the prescriber if use feels difficult to control or continues for reasons other than pain relief.
Sources for this answer
- Tapentadol Aspire 250 mg prolonged-release tablets — Current selected SmPCemc · Summary of Product Characteristics
- Tapentadol Neuraxpharm 150 mg prolonged-release capsules, hard — Current selected SmPCemc · Summary of Product Characteristics