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Medicines protamine sulfateQuestion & answer

protamine sulfate · Medicine question

Can protamine sulfate cause a slow heart rate?

iatroX medicinesPublished 8 November 2026

The answer

Answer

Yes, protamine sulfate can cause bradycardia (a slow heart rate).

Sources for this answer

Prosulf 10mg/ml Solution for InjectionWockhardt UK Ltd · emc · SmPC §4.8 Undesirable effects · Version 6Document updated 9 May 2018

Sources checked 8 November 2026

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The full medicine guide

protamine sulfate

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