Answer
Yes, prolonged midazolam sedation in intensive care may cause physical dependence, with risk increasing with dose and treatment duration and being greater in patients with a history of alcohol or drug abuse.
Sources for this answer
- Midazolam 5mg in 1ml InjectionADVANZ Pharma · emc · SmPC §4.4 Special warnings and precautions for use · Version 9Document updated
Sources checked