Answer
Yes, decreased appetite occurred in pivotal trials of Esbriet (pirfenidone) and was generally manageable without significant consequences, but uncommonly it was associated with significant weight loss requiring medical intervention.
Sources for this answer
- Esbriet 267 mg, 801 mg Film-coated TabletsRoche Products Limited · emc · SmPC §4.8 Undesirable effects · Version 14Document updated
Sources checked