Answer
Methylnaltrexone bromide should not be used during pregnancy unless clearly necessary, because adequate data in pregnant women are lacking, animal studies showed reproductive toxicity at high doses, and the potential human risk is unknown.
Sources for this answer
- Relistor 12mg/0.6ml solution for injection vialsBausch Health Ireland Limited · emc · SmPC §4.6 Fertility, pregnancy and lactation · Version 1Document updated
Sources checked