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Medicines folic acidQuestion & answer

folic acid · Medicine question

Can methylfolate replace folic acid in pregnancy?

iatroX medicinesPublished 13 August 2026Reviewed 13 August 2026

The answer

Answer

Evidence that methylfolate prevents neural-tube defects is insufficient, so UK pregnancy information continues to recommend folic acid.

Sources for this answer

UK Teratology Information ServiceUK Teratology Information Service · Reputable Web

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folic acid

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