Answer
Yes. Tramadol is an opioid, and repeated use can cause tolerance, dependence or opioid use disorder, even at therapeutic amounts. Contact the prescriber if use feels difficult to control.
Sources for this answer
- Skudexa 75 mg/25 mg film-coated tablets — Current selected SmPCemc · Summary of Product Characteristics
General medicine information. Follow the instructions for your own medicine and speak to a pharmacist or clinician about your individual circumstances.