imatinib mesilate · Medicine question

Can imatinib cause liver injury or liver failure?

iatroX medicinesPublished 8 November 2026

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Yes, liver injury, including liver failure and hepatic necrosis, has been observed with imatinib, and serious hepatic reactions have increased when imatinib is combined with high-dose chemotherapy.

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GLIVEC film-coated tabletsNovartis Pharmaceuticals UK Ltd · emc · SmPC §4.4 Special warnings and precautions for use · Version 41Document updated 4 February 2026

Sources checked 8 November 2026

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