skip to main content

brainstorm askiatroX medicines

simulations beta

loading page…

learn & practise

exams international doctors free questions Socratic Tutor rounds stat clinical connections academy journal tool guides

clinical reference

askiatroX knowledge centre medicines UK / NICE guidance international guidance calculators q&a library

trust & support

how it works methodology account & support frequently asked questions about us clinical safety consultancy

legal

mobile app · scan to download

Medicines allopurinolQuestion & answer

allopurinol · Medicine question

Can I take allopurinol with azathioprine or mercaptopurine?

iatroX medicinesPublished 13 August 2026Reviewed 13 August 2026

The answer

Answer

Only under specialist supervision because allopurinol can greatly increase thiopurine exposure and cause life-threatening bone-marrow suppression.

Sources for this answer

Allopurinol Tablets BP 100mgemc · SmPC Current selected SmPC · Version 3
Allopurinol 100mgemc · SmPC Current selected SmPC · Version 3

Explore this learning need in CPDTake this topic to CPD, then choose your learning context and available question library.

The full medicine guide

allopurinol

Read the wider context, including uses, precautions and the sources behind this medicine guide.

Read the allopurinol guide

More clinical questions?

Explore the tools and reference material available on iatroX.

Explore askiatroX

More questions about allopurinol

Does allopurinol relieve gout-attack pain?Why can gout attacks happen after starting allopurinol?Should I stop allopurinol if I develop a rash?Can allopurinol affect the kidneys?Can allopurinol affect the liver or blood cells?Can I take amoxicillin with allopurinol?