Answer
Oxipurinol is cleared through the kidneys, so impaired kidney function can increase exposure and hypersensitivity risk.
Sources for this answer
- Allopurinol Tablets BP 100mg — Current selected SmPCemc · Summary of Product Characteristics
- Allopurinol 100mg — Current selected SmPCemc · Summary of Product Characteristics
General medicine information. Follow the instructions for your own medicine and speak to a pharmacist or clinician about your individual circumstances.