Answer
Yes, Depo-Medrone (methylprednisolone acetate) can infrequently cause dermal or subdermal changes forming skin depressions at the injection site, with regeneration usually complete within a few months or after all steroid crystals have been absorbed.
Sources for this answer
- Depo-Medrone 40mg/ml Suspension for InjectionPfizer Limited · emc · SmPC §4.4 Special warnings and precautions for use · Version 30Document updated
Sources checked