Answer
Not directly. They release levodopa differently and have different administration requirements, so changes should be planned and monitored by the specialist team.
Sources for this answer
- Sinemet 12.5mg/50mg, 10mg/100mg, 25mg/100mg and 25mg/250mg Tablets — Current selected SmPCemc · Summary of Product Characteristics
- Sinemet CR and Half Sinemet CR — Current selected SmPCemc · Summary of Product Characteristics
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