Why should the Baxter Healthcare Ltd product Potassium Chloride 0.15% w/v and Glucose 10% w/v Solution for Infusion BP be administered through a large peripheral or central vein?

The Baxter Healthcare Ltd product Potassium Chloride 0.15% w/v and Glucose 10% w/v Solution for Infusion BP requires a large peripheral or central vein to reduce potassium-related sclerosis risk; during central infusion, the catheter must not be in the atrium or ventricle, to avoid localised hyperkalaemia.