Answer
St John's wort should be avoided with dabrafenib mesilate because it is a potent inducer of CYP2C8 or CYP3A4, which is likely to decrease dabrafenib concentrations.
Sources for this answer
- Tafinlar 50 mg & 75 mg hard capsulesNovartis Pharmaceuticals UK Ltd · emc · SmPC §4.5 Interaction with other medicinal products · Version 40Document updated
Sources checked