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Medicines ceritinibQuestion & answer

ceritinib · Medicine question

Why should St John's wort be avoided during ceritinib treatment?

iatroX medicinesPublished 8 November 2026

The answer

Answer

St John's wort should be avoided during ceritinib treatment because it is a strong CYP3A inducer that can decrease ceritinib plasma concentrations.

Sources for this answer

Zykadia 150mg Film-coated TabletsNovartis Pharmaceuticals UK Ltd · emc · SmPC §4.5 Interaction with other medicinal products · Version 3Document updated 21 July 2021

Sources checked 8 November 2026

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ceritinib

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