Answer
Pazopanib hydrochloride should not be used in children younger than two years because its mechanism of action can severely affect organ growth and maturation during early postnatal development, as demonstrated in rodents.
Sources for this answer
- Votrient 200 mg and 400 mg film coated tabletsNovartis Pharmaceuticals UK Ltd · emc · SmPC §4.4 Special warnings and precautions for use · Version 36Document updated
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