Answer
Meropenem and valproic acid should not be used together because carbapenems can reduce valproic acid blood levels by 60–100% within about two days, an interaction considered unmanageable because of its speed and magnitude.
Sources for this answer
- Meronem IV 500mgPfizer Limited · emc · SmPC §4.5 Interaction with other medicinal products · Version 18Document updated
Sources checked