Answer
Cigarette smoking reduces riociguat exposure. Starting or stopping smoking can therefore alter its effect and may require specialist review.
Sources for this answer
- Adempas 0.5 mg, 1.0 mg, 1.5 mg, 2.0 mg, 2.5 mg film-coated tablets — Current selected SmPCemc · Summary of Product Characteristics
General medicine information. Follow the instructions for your own medicine and speak to a pharmacist or clinician about your individual circumstances.