Answer
Grapefruit can inhibit CYP3A and raise entrectinib concentrations, increasing the risk of adverse effects. Seville oranges should also be avoided.
Sources for this answer
- Rozlytrek 100 mg & 200 mg hard capsules — Current selected SmPCemc · Summary of Product Characteristics
General medicine information. Follow the instructions for your own medicine and speak to a pharmacist or clinician about your individual circumstances.