Answer
Daratumumab can make antibody screening and crossmatching appear positive and may mask other antibodies. ABO and Rh typing remain unaffected, but advance notice helps the laboratory select compatible blood safely.
Sources for this answer
- DARZALEX 1,800 mg solution for injection — Current selected SmPCemc · Summary of Product Characteristics
- DARZALEX 20 mg/mL concentrate for solution for infusion — Current selected SmPCemc · Summary of Product Characteristics
General medicine information. Follow the instructions for your own medicine and speak to a pharmacist or clinician about your individual circumstances.