daratumumab · Medicine question

Why must blood-transfusion staff know?

iatroX medicinesPublished 19 August 2026Reviewed 19 August 2026

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Daratumumab can make antibody screening and crossmatching appear positive and may mask other antibodies. ABO and Rh typing remain unaffected, but advance notice helps the laboratory select compatible blood safely.

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DARZALEX 1,800 mg solution for injectionemc · SmPC Current selected SmPC · Version 25
DARZALEX 20 mg/mL concentrate for solution for infusionemc · SmPC Current selected SmPC · Version 34

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