Answer
Ibrutinib can temporarily move malignant lymphocytes from tissues into the bloodstream. In chronic lymphocytic leukaemia and mantle cell lymphoma, this expected effect does not by itself mean the cancer is worsening.
Sources for this answer
- IMBRUVICA 560 mg film-coated tablets (Great Britain) — Current selected SmPCemc · Summary of Product Characteristics
General medicine information. Follow the instructions for your own medicine and speak to a pharmacist or clinician about your individual circumstances.