Answer
Lumasiran is targeted to liver cells, and moderate or severe hepatic impairment may reduce its effect; efficacy should therefore be monitored.
Sources for this answer
- Oxlumo 94.5 mg/0.5 mL solution for injection — Current selected SmPCemc · Summary of Product Characteristics
General medicine information. Follow the instructions for your own medicine and speak to a pharmacist or clinician about your individual circumstances.